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[1] A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism. 

     发表于:iScience. 2022PMCID: PMC9249674  IF=6.107


[2]Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses. 

     发表于:Genomics Proteomics Bioinformatics. 2021. PMCID: PMC8578027 IF=6.409


[3]Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression.

     发表于:J Exp Clin Cancer Res. 2020 PMCID: PMC7203840 IF=13.801


[4]SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury

     发表于:iScience. 2021 PMCID: PMC8169952 IF=6.107


[5]BRD4 inhibitor GNE987 exerts anti-cancer effects by targeting super-enhancers in neuroblastoma.

     发表于:Cell Biosci. 2022 PMCID: PMC8932231 IF=9.584


[6]circ-NOL10 regulated by MTDH/CASC3 inhibits breast cancer progression and metastasis via multiple miRNAs and PDCD4.

     发表于:Mol Ther Nucleic Acids. 2021 PMCID: PMC8526500 IF=10.183


[7]A pan-cancer analysis of CpG Island gene regulation reveals extensive plasticity within Polycomb target genes.

     发表于:Nat Commun. 2021 PMCID: PMC8087678 IF=17.694


[8]Impairment of APPL1/Myoferlin facilitates adipogenic differentiation of mesenchymal stem cells by blocking autophagy flux in osteoporosis.

     发表于:Cell Mol Life Sci. 2022 PMCID: PMC9391247 IF=9.207


[9]Transcription factor EB-mediated mesenchymal stem cell therapy induces autophagy and alleviates spinocerebellar ataxia type 3 defects in neuronal cells model.

     发表于:Cell Death Dis. 2022 PMCID: PMC9293975 IF=9.685


[10]Circular RNA circPICALM sponges miR-1265 to inhibit bladder cancer metastasis and influence FAK phosphorylation.

     发表于:EBioMedicine. 2019 PMCID: PMC6838432 IF=11.205


[11]CLP36 promotes p53 deficient sarcoma progression through suppression of atrophin-1 interacting protein-4 (AIP-4)-dependent degradation of YAP1.

     发表于:Theranostics. 2022 PMCID: PMC9274740 IF=11.6


[12]Blocking STAT3 signaling augments MEK/ERK inhibitor efficacy in esophageal squamous cell carcinoma.

     发表于:Cell Death Dis. 2022  PMCID: PMC9132929 IF=9.685


[13]AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.

     发表于:Nucleic Acids Res. 2022  PMCID: PMC9122597 IF=19.16

     引用服务/产品:普通引物合成Qubit dsDNA HS Assay mix Kits

[14]Generation of individualized immunocompatible endothelial cells from HLA-I-matched human pluripotent stem cells.

     发表于:Stem Cell Res Ther. 2022  PMCID: PMC8812039 IF=8.079


[15]INPP5F translocates into cytoplasm and interacts with ASPH to promote tumor growth in hepatocellular carcinoma.

     发表于:J Exp Clin Cancer Res. 2022 PMCID: PMC8740451  IF=13.801


[16]P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer.

     发表于:Cancer Commun (Lond). 2021 PMCID: PMC8696220 IF=15.283


[17]MicroRNA-361-Mediated Inhibition of HSP90 Expression and EMT in Cervical Cancer Is Counteracted by Oncogenic lncRNA NEAT1.

     发表于:Cells. 2020 PMCID: PMC7140536 IF=7.666


[18]D609 protects retinal pigmented epithelium as a potential therapy for age-related macular degeneration.

     发表于:Signal Transduct Target Ther. 2020  PMCID: PMC7054264 IF=38.104


[19]A sensitive, accurate, and high-throughput gluco-oligosaccharide oxidase-based HRP colorimetric method for assaying lytic polysaccharide monooxygenase activity

     发表于:Biotechnol Biofuels Bioprod. 2022  PMCID: PMC8830019 IF=7.67


[20]Osteogenic differentiation of mesenchymal stem cells promotes c-Jun-dependent secretion of interleukin 8 and mediates the migration and differentiation of CD4+ T cells.

     发表于:Stem Cell Res Ther. 2022 PMCID: PMC8818240 IF=8.079


[21]Long noncoding RNA DIO3OS interacts with miR-122 to promote proliferation and invasion of pancreatic cancer cells through upregulating ALDOA.

     发表于:Cancer Cell Int. 2019 PMCID: PMC6668142 IF=6.429


[22]The EGFR‐P38 MAPK axis up‐regulates PD‐L1 through miR‐675‐5p and down‐regulates HLA‐ABC via hexokinase‐2 in hepatocellular carcinoma cells.

     发表于:Cancer Commun (Lond). 2021 PMCID: PMC7819566 IF=15.283


[23]Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission.

     发表于:Theranostics. 2021 PMCID: PMC7778598 IF=11.6


[24]LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling.

     发表于:Cell Death Dis. 2018  PMCID: PMC7778598 IF=7.109

     引用服务/产品:克隆构建基因合成shRNA 设计及构建

[25]DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1.

     发表于:Nucleic Acids Res. 2018  PMCID: PMC6009666 IF=19.16


[26]Hemi-methylated CpG sites connect Dnmt1-knockdown-induced and Tet1-induced DNA demethylation during somatic cell reprogramming.

     发表于:Cell Discov. 2019 PMCID: PMC6370818  IF=38.079


[27]A humanized TCR retaining authentic specificity and affinity conferred potent anti‐tumour cytotoxicity.

     发表于:Immunology. 2018 PMCID: PMC6099166  IF=7.215


[28]HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5-WDR5-dependent transcriptional program.

     发表于:Cancer Commun (Lond). 2022 PMCID: PMC9118058  IF=15.283

     引用服务/产品:克隆构建基因合成shRNA 设计及构建

[29]LncRNA LINC01537 Promotes Gastric Cancer Metastasis and Tumorigenesis by Stabilizing RIPK4 to Activate NF-κB Signaling.

     发表于:Cancers (Basel). 2022  PMCID: PMC9657364 IF=6.575


[30]The Novel Protein ADAMTS16 Promotes Gastric Carcinogenesis by Targeting IFI27 through the NF-κb Signaling Pathway.

     发表于:Int J Mol Sci. 2022  PMCID: PMC9570124 IF=6.208

     引用服务/产品:克隆构建基因合成shRNA 设计及构建

[31]PSMD2 contributes to the progression of esophageal squamous cell carcinoma by repressing autophagy.

     发表于:Cell Biosci. 2023 PMCID: PMC10061715 IF=9.584


[32]Anchoring super-enhancer-driven oncogenic lncRNAs for anti-tumor therapy in hepatocellular carcinoma.

     发表于:Mol Ther. 2022 PMID: 36461633 IF=12.91


[33]Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR-671-5p/LGALS3BP/NF-κB axis.

     发表于:Cancer Sci. 2023 PMID: 37186007 IF=6.518


[34]HHMMR promotes prostate cancer proliferation and metastasis via AURKAmTORC2E2F1 positive feedback loop.

     发表于:Cell Death Discov. 2023 PMCID: PMC9905489 IF=7.109


[35]HPV Enhances HNSCC Chemosensitization by Inhibiting SERPINB3 Expression to Disrupt the Fanconi Anemia Pathway.

     发表于:Adv Sci (Weinh). 2022  PMCID: PMC9811475 IF=17.521

     引用服务/产品:克隆构建基因合成shRNA 设计及构建

[36]PINK1-Mediated Mitophagy Promotes Oxidative Phosphorylation and Redox Homeostasis to Induce Drug-Tolerant Persister Cancer Cells.

     发表于:Cancer Res. 2023  PMID: 36480196 IF=13.312

     引用服务/产品:克隆构建基因合成shRNA 设计及构建

[37]Profle of chimeric RNAs and TMPRSS2‑ERG e2e4 isoform in neuroendocrine prostate cancer.

     发表于:Cell Biosci. 2022 PMCID: PMC9463804 IF=9.58


[38]RNA-binding protein MEX3A controls G1S transition via regulating the RBE2F pathway in clear cell renal cell carcinoma.

     发表于:Mol Ther Nucleic Acids. 2021  PMCID: PMC8703191  IF=10.183


[39]SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion.

     发表于:J Transl Med. 2023  PMCID: PMC10161564  IF=8.44


[40]ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems.

     发表于:BMC Biol. 2020  PMCID: PMC7510086 IF=7.364

     引用服务/产品:CRISPR sgRNA 文库服务

[41]CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.

     发表于:Mol Ther. 2021  PMCID: PMC7934638 IF=12.91

     引用服务/产品:CRISPR sgRNA 文库服务

[42]Identification of Peptoniphilus vaginalis-Like Bacteria,Peptoniphilus septimus sp.nov., From Blood Cultures in a Cervical Cancer Patient Receiving Chemotherapy: Case and Implications.

     发表于:Front Cell Infect Microbiol. 2022   PMCID: PMC9307962 IF=6.073

     引用服务/产品:动植物基因组de novo 测序

[43]Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model.

     发表于:Mol Ther Nucleic Acids. 2019  PMCID: PMC6849368 IF=10.183


[44]Loss of the RNA trimethylguanosine cap is compatible with nuclear accumulation of spliceosomal snRNAs but not pre-mRNA splicing or snRNA processing during animal development.

     发表于:LoS Genet. 2020  PMCID: PMC7605716 IF=6.02

     引用服务/产品:小RNA 测序

[45]Efficient RNA drug delivery using red blood cell extracellular vesicles.

     发表于:Nat Commun. 2018  PMCID: PMC6004015 IF=17.694


[46]Precise A•T to G•C base editing in the zebrafish genome.

     发表于:BMC Biol. 2018  PMCID: PMC6247682 IF=7.364


[47]Genome-wide profiling of adenine base editor specificity by EndoV-seq.

     发表于:Nat Commun. 2019  PMCID: PMC6325126 IF=17.694


[48]Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis.

     发表于:Molecular Cancer. 2019  PMCID: PMC652424 IF=44.144


[49]circRIP2 accelerates bladder cancer progression via miR-1305/Tgf-β2/smad3 pathway.

     发表于:Molecular Cancer. 2020  PMCID: PMC6998850 IF=44.144


[50]A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease.

     发表于:Cell. 2018  PMCID: PMC5935586 IF=66.85


[51]A CRISPR–Cas9-triggered strand displacement amplifification method for ultrasensitive DNA detection.

     发表于:Nat Commun. 2018  PMCID: PMC6258682 IF=17.694


[52]Quinoline Derivatives Kill Mycobacterium tuberculosis by Activating Glutamate Kinase.

     发表于:Cell Chem Biol. 2019  PMID: 31204286 IF=9.039


[53]A standard for near-scarless plasmid construction using reusable DNA parts.

     发表于:Nat Commun. 2019  PMCID: PMC6650416 IF=17.694


[54]Dual-CRISPR/Cas12a-Assisted RT-RAA for Ultrasensitive SARS-CoV‑2 Detection on Automated Centrifugal Microfluidics.

     发表于:Anal Chem2022   PMID: 35775831 IF=8.008


[55]Fn-Dps, a novel virulence factor of Fusobacterium nucleatum, disrupts erythrocytes and promotes metastasis in colorectal cancer.

     发表于:PLoS Pathog. 2023  PMCID: PMC9873182 IF=7.464

     引用服务/产品:小RNA 测序

[56]Urolithin A protects against acetaminophen-induced liver injury in mice via sustained activation of Nrf2.

     发表于:Int J Biol Sci. 2022  PMCID: PMC8935220 IF=10.75

     引用服务/产品:小RNA 测序

[57]CD98hc has a pivotal role in maintaining the immuno-barrier integrity of basal layer cells in esophageal epithelium.

     发表于:Cancer Cell Int. 2022  PMCID: PMC8864845 IF=6.429


[58]Two cGAS-like receptors induce antiviral immunity in Drosophila.

     发表于:Nature. 2021  PMID: 34261128 IF=69.504


[59]Bioengineered bacterial outer membrane vesicles encapsulated Polybia–mastoparan I fusion peptide as a promising nanoplatform for bladder cancer immunemodulatory chemotherapy.

     发表于:Front Immunol. 2023  PMCID: PMC10043419 IF=8.786


[60]Isolation and identifification of a salt-tolerant aerobic denitrifying bacterial strain and its application to saline wastewater treatment in constructed wetlands.

     发表于:Bioresour Technol. 2019  PMID: 31301568  IF=11.889


[61]Effificient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor.

     发表于:Cells. 2022  PMCID: PMC9776866  IF=7.666


[62]The Atypical MAP Kinase MAPK15 Is Required for Lung Adenocarcinoma Metastasis via Its Interaction with NF-κB p50 Subunit and Transcriptional Regulation of Prostaglandin E2 Receptor EP3 Subtype.

     发表于:Cancers (Basel). 2023  PMCID: PMC10000388  IF=6.575


[63]A Meloidogyne graminicola PectateLyase ls Involved in Virulence andActivation of Host DefenseResponses.

     发表于:Front Plant Sci. 2021  PMCID: PMC8044864  IF=6.627


[64]Eliminating predictable DNA off-targeteffects of cytosine base editor by using duaguiders including sgRNA and TALE.

     发表于:Mol Ther. 2022  PMCID: PMC9263286   IF=12.91


[65]Microfluidic synthesis of manganese-alginate nanogels with self-supplyingHO2 capability for synergistic chemo/chemodynamic therapy andboosting anticancer immunity.

     发表于:Chemical Engineering Journal.https://doi.org/10.1016/j.cej.2022.134926  IF=16.744

     引用服务/产品:小RNA 测序

[66]HNF4A-BAP31-VDAC1 axis synchronously regulates cellproliferation and ferroptosis in gastric cancer.

     发表于:Cell Death Dis. 2023  PMCID: PMC10256786  IF=9.685


[67]SERPINA3-ANKRD11-HDAC3 pathway induced aromatase inhibitor resistance in breast cancer can be reversed by HDAC3 inhibition.

     发表于:Commun Biol. 2023   PMCID: PMC10326080  IF=6.548


[68]Inhibition of phosphoglycerate dehydrogenase induces ferroptosis and overcomes enzalutamide resistance in castration-resistant prostate cancer cells .

     发表于:Drug Resist Updat. 2023  PMID: 37423117  IF=24.3


[69]Transmembrane nuclease NUMEN/ENDOD1 regulates DNA repair pathway choice at the nuclear periphery.

     发表于:Nat Cell Biol. 2023  PMID: 37322289  IF=28.213


[70]Decrotonylation of AKT1 promotes AKT1 phosphorylation and activation during myogenic differentiation.

     发表于:J Adv Res. 2023 PMCID: PMC10403674  IF=10.7


[71]Upregulated LncRNA H19 Sponges MiR-106a- 5p and Contributes to Aldosterone-Induced Vascular Calcification via Activating the Runx2- Dependent Pathway.

     发表于:Arterioscler Thromb Vasc Biol. 2023  PMID: 37409531  IF=10.514

     引用服务/产品:克隆构建基因合成siRNA 转染试剂

[72]UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.

     发表于:Cell Death Dis. 2023   PMCID: PMC10329682  IF=9.685


[73]Establishing an hTERT-driven immortalized umbilical cord-derived mesenchymal stem cell line and its therapeutic application in mice with liver failure.

     发表于:J Tissue Eng. 2023 PMCID: PMC10510347  IF=8.2


[74]FTO-targeted siRNA delivery by MSC-derived exosomes synergistically alleviates dopaminergic neuronal death in Parkinson’s disease via m6A-dependent regulation of ATM mRNA.

     发表于:J Transl Med. 2023 PMCID: PMC10515429  IF=7.4


[75]Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.

     发表于:J Transl Med. 2023 PMCID: PMC10536727  IF=7.4


[76]Methionine orchestrates the metabolism vulnerability in cisplatin resistant bladder cancer microenvironment.

     发表于:Cell Death Dis. 2023  PMCID: PMC10427658  IF=9.685


[77]The APCC E3 ligase subunit ANAPC11 mediates FOXO3 protein degradation to promote cell proliferation and lymph node metastasis in urothelial bladder cancer.

     发表于:Cell Death Dis. 2023  PMCID: PMC10423259  IF=9.685


[78]Thioredoxin-interacting protein-activated intracellular potassium deprivation mediates the anti-tumour effect of a novel histone acetylation inhibitor HL23, a fangchinoline derivative, in human hepatocellular carcinoma.

     发表于:Adv Res. 2023  PMCID: PMC10491973  IF=10.7

     引用服务/产品:克隆构建基因合成shRNA 设计及构建

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